Hearing icon
Signia™ AX

60-day free trial

Hearing icon
Resound™ One

60-day free trial

Hearing icon
Phonak™ Paradise

60-day free trial

Hearing icon
Online Care

Online Free Hearing Test

Hearing icon
In-Office Care

In-Person Test - Orland

HOW DOES HEARING LOSS IMPACT THE BRAIN?

Happy couple

Daniela Beckmann, Mirko Feldmann, Olena Shchyglo, and Professor Denise Manahan-Vaughan from the Department of Neurophysiology of the Medical Faculty worked together for the study.

When sensory perception fades

The researchers studied the brain of mice that exhibit hereditary hearing loss, similar to age-related hearing loss in humans. The scientists analyzed the density of neurotransmitter receptors in the brain that are crucial for memory formation. They also researched the extent to which information stored in the brain’s most important memory organ, the hippocampus, was affected.

Adaptability of the brain suffers

Memory is enabled by a process called synaptic plasticity. In the hippocampus, synaptic plasticity was chronically impaired by progressive hearing loss. The distribution and density of neurotransmitter receptors in sensory and memory regions of the brain also changed constantly. The stronger the hearing impairment, the poorer were both synaptic plasticity and memory ability.

“Our results provide new insights into the putative cause of the relationship between cognitive decline and age-related hearing loss in humans,” said Denise Manahan-Vaughan. “We believe that the constant changes in neurotransmitter receptor expression caused by progressive hearing loss create shifting sands at the level of sensory information processing that prevent the hippocampus from working effectively”, she adds.

Funding

The study was funded by the Collaborative Research Center (SFB) 874 of the German Research Foundation. SFB 874 “Integration and Representation of Sensory Processes” has existed at RUB since 2010. The researchers investigate how sensory signals generate neuronal maps, resulting in complex behavior and memory formation. Daniela Beckmann and Mikro Feldmann have also completed the medical students’ program of the SFB 874 and the International Graduate School of Neuroscience.

Related Articles

You might be interested in...

Hearing

BRIEF POSTNATAL BLINDNESS TRIGGERS LONG-LASTING REORGANIZATION IN THE BRAIN

Temporary visual deprivation shortly after birth induces permanent auditory responses in the visual area of the brain, highlighting a crossmodal competition for brain territories during […]

Read More →
Ear Grid

SAY WHAT? HOW THE BRAIN SEPARATES OUR ABILITY TO TALK AND WRITE

Out loud, someone says, “The man is catching a fish.” The same person then takes pen to paper and writes, “The men is catches a […]

Read More →

UB RESEARCHERS TAKE IMPORTANT STEPS TOWARD UNDERSTANDING HOW ANIMALS MAKE SENSE OF THE AUDITORY WORLD

BUFFALO, N.Y. – Sit down with a friend in a quiet restaurant and begin talking, just before the dinner crowd’s arrival. Business is slow at first, […]

Read More →